Abstract

The aims of this study were: to document sleep disturbances in individuals with Phelan-McDermid syndrome, to assess whether these individuals had been evaluated for sleep disorders, and to examine relationships between the sleep behavior of these individuals and the sleep behavior and daytime functioning of their caregivers.Participants were 193 caregivers of individuals with Phelan-McDermid Syndrome recruited by the Phelan-McDermid Syndrome Foundation. Data were collected via a survey comprising two questionnaires: the Children's Sleep Habits Questionnaire and the Parents' Sleep Habits Questionnaire. Data were analyzed using multiple linear regression analyses, Pearson correlation analyses, and independent-samples t-tests.Ninety percent of individuals with Phelan-McDermid Syndrome showed evidence of marked sleep disturbance based on caregiver responses to the Children's Sleep Habits Questionnaire. However, only 22% of individuals had undergone a formal sleep assessment. Reported increased sleep disturbance in individuals with Phelan-McDermid Syndrome was a statistically significant predictor of reported increased sleep disturbance and daytime sleepiness in their Caregivers.Sleep disturbance may be present in a substantial proportion of individuals with Phelan-McDermid Syndrome and is negatively associated with caregivers' wellbeing. However, most individuals with Phelan-McDermid Syndrome have not been evaluated for sleep disorders. When properly diagnosed, many sleep disorders can be alleviated with intervention. Thus, routine screening for and evaluation of sleep disturbances in individuals with Phelan-McDermid Syndrome may have long-term positive impacts on the wellbeing of these individuals and their caregivers.

View details for PubMedID 27923425