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Stanford Health Care

Outcomes and patterns of care of patients with locally advanced oropharyngeal carcinoma treated in the early 21st century RADIATION ONCOLOGY Garden, A. S., Kies, M. S., Morrison, W. H., Weber, R. S., Frank, S. J., Glisson, B. S., Gunn, G. B., Beadle, B. M., Ang, K. K., Rosenthal, D. I., Sturgis, E. M. 2013; 8

Abstract

We performed this study to assess outcomes of patients with oropharyngeal cancer treated with modern therapy approaches.Demographics, treatments and outcomes of patients diagnosed with Stage 3- 4B squamous carcinoma of the oropharynx, between 2000-2007 were tabulated and analyzed.The cohort consisted of 1046 patients. The 5-year actuarial overall survival, recurrence-free survival and local-regional control rates for the entire cohort were 78%, 77% and 87% respectively. More advanced disease, increasing T-stage and smoking were associated with higher rates of local-regional recurrence and poorer survival.Patients with locally advanced oropharyngeal cancer have a relatively high survival rate. Patients' demographics and primary tumor volume were very influential on these favorable outcomes. In particular, patients with small primary tumors did very well even when treatment was not intensified with the addition of chemotherapy.

View details for DOI 10.1186/1748-717X-8-21

View details for Web of Science ID 000315408100001

View details for PubMedID 23360540

View details for PubMedCentralID PMC3576243