Recurrent oral cavity cancer: Patterns of failure after salvage multimodality therapy. Head & neck Quinlan-Davidson, S. R., Morrison, W. H., Myers, J. N., Gunn, G. B., William, W. N., Beadle, B. M., Skinner, H. D., Gillenwater, A. M., Frank, S. J., Phan, J., Johnson, F. M., Fuller, C. D., Zafereo, M. E., Rosenthal, D. I., Garden, A. S. 2016


We focused on a cohort of radiation naïve patients who had recurrent oral cavity cancer (recurrent OCC) to assess their outcomes with salvage multimodal therapy.A retrospective single institutional study was performed of patients with recurrent OCC. Disease recurrence and survival outcomes were assessed.Seventy-eight patients were analyzed. All patients had salvage surgery and intensity-modulated radiotherapy (IMRT) and 74% had chemotherapy. Five-year overall survival, recurrence-free survival, and locoregional control rates were 59%, 60%, and 74%, respectively.Outcomes of radiation naïve patients with recurrent OCC are fair, and seem similar with patients with locally advanced nonrecurrent OCC treated with multimodal therapy. © 2016 Wiley Periodicals, Inc. Head Neck, 2016.

View details for DOI 10.1002/hed.24666

View details for PubMedID 28006086