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Neprilysin Inhibitors in Cardiovascular Disease. Current cardiology reports Kang, G., Banerjee, D. 2017; 19 (2): 16-?

Abstract

Mortality from heart failure remains high despite advances in medical therapy over the last three decades. Angiotensin receptor-neprilysin inhibitor (ARNI) combinations are the latest addition to the heart failure medical armamentarium, which is built on the cornerstone regimen of beta blockers, angiotensin converting enzyme (ACE) inhibitors/angiotensin receptor blockers, and aldosterone antagonists. Recent trial data have shown a significant mortality benefit from ARNIs, which, as of May 2016, have now received a class I recommendation for use in patients with heart failure and reduced ejection fraction from the major American and European cardiology societies.

View details for DOI 10.1007/s11886-017-0827-0

View details for PubMedID 28185171