Leveraging genomic data in smoking cessation trials in the era of Precision Medicine: Why and how. Nicotine & tobacco research Chen, L., Zawertailo, L., Piasecki, T. M., Kaprio, J., Foreman, M., Elliott, H. R., David, S. P., Bergen, A. W., Baurley, J. W., Tyndale, R. F., Baker, T. B., Bierut, L. J., Saccone, N. L. 2017


This paper outlines a framework for the consistent integration of biological data/samples into smoking cessation pharmacotherapy trials, aligned with the objectives of the recently unveiled Precision Medicine Initiative. Our goal is to encourage and provide support for treatment researchers to consider biosample collection and genotyping their existing samples, as well as integrating genetic analyses into their study design in order to realize precision medicine in treatment of nicotine dependence.

View details for DOI 10.1093/ntr/ntx097

View details for PubMedID 28498934