Gastrinomas: Medical or Surgical Treatment. Endocrinology and metabolism clinics of North America Norton, J. A., Foster, D. S., Ito, T., Jensen, R. T. 2018; 47 (3): 577–601

Abstract

This article reviews the role of surgical and medical management in patients with Zollinger-Ellison syndrome (ZES) due to a gastrin-secreting neuroendocrine tumor (gastrinoma). It concentrates on the status at present but also briefly reviews the changes over time in treatment approaches. Generally, surgical and medical therapy are complementary today; however, in some cases, such as patients with ZES and multiple endocrine neoplasia type 1, the treatment approach remains controversial.

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