Outer Retinal Defects Represent a Normal Recovery Pathway Following Internal Limiting Membrane Peeling in Macular Hole Surgery OPHTHALMIC SURGERY LASERS & IMAGING RETINA Powers, M. A., Shields, R. A., Moshfeghi, A. A., Moshfeghi, D. M. 2018; 49 (9): E1–E8


To examine perioperative factors associated with the development of outer retinal defects (ORDs) following surgical repair of macular holes (MHs).An institutional review board-approved, retrospective, interventional cohort study was conducted. Patients who underwent MH repair during a 5-year period were identified. Statistical analysis was conducted to detect significant perioperative associations to ORD development.One hundred twenty-four eyes were included, and 54% developed an ORD following surgery. These defects correlated with lower preoperative stage (P = .0057), preoperative phakia (P = .036), and lack of prior macular surgery (P = .0016). Patients in the ORD group had significantly better preoperative and postoperative visual acuity (P = .031 and P = .0004, respectively), but there was no difference in change in acuity from preoperatively to 3 months postoperatively when compared with control patients (P = 42). The majority (89%) of ORDs resolved by 24 months postoperatively.The development of ORDs appears to be correlated with several factors indicative of favorable overall eye health and less advanced pathology and may represent a normal state of recovery after MH repair with internal limiting membrane peeling. [Ophthalmic Surg Lasers Imaging Retina. 2018;49:e1-e8.].

View details for DOI 10.3928/23258160-20180907-01

View details for Web of Science ID 000444831000001

View details for PubMedID 30222813