Surgical Therapy INTRACRANIAL ATHEROSCLEROSIS: PATHOPHYSIOLOGY, DIAGNOSIS AND TREATMENT Oh, C., Steinberg, G. K., Kim, J. S., Caplan, L. R., Wong, K. S. 2016; 40: 164–78


Many prior investigations have indicated the important role of medical treatment to prevent stroke in patients with intracranial atherosclerosis, with angioplasty and stenting occasionally being performed. In a subgroup of patients with severe hemodynamic impairment, extracranial-intracranial (EC-IC) bypass surgery may be considered. Additionally, in patients with massive infarctions due to middle cerebral artery (MCA) occlusion, the use of decompressive craniectomy may lower mortality rates and improve long-term quality of life. However, the benefit of these surgical procedures in patients with intracranial atherosclerosis has long been controversial. In this chapter, we review the surgical therapies for patients with intracranial atherosclerosis. This review does not include EC-IC bypass surgery for moyamoya disease, which is discussed in another chapter.

View details for DOI 10.1159/000448312

View details for Web of Science ID 000411854800013

View details for PubMedID 27960189