Automatically Determining the Confocal Parameters From OCT B-Scans for Quantification of the Attenuation Coefficients IEEE TRANSACTIONS ON MEDICAL IMAGING Dwork, N., Smith, G. T., Leng, T., Pauly, J. M., Bowden, A. K. 2019; 38 (1): 261–68


The attenuation coefficient is a relevant biomarker for many diagnostic medical applications. Recently, the Depth-Resolved Confocal (DRC) technique was developed to automatically estimate the attenuation coefficients from Optical Coherence Tomography (OCT) data with pixel-level resolution. However, DRC requires that the confocal function parameters (i.e., focal plane location and apparent Rayleigh range) be known a priori. In this paper, we present the autoConfocal algorithm: a simple, automatic method for estimating those parameters directly from OCT imagery when the focal plane is within the sample. We present autoConfocal+DRC results on phantom data, ex-vivo biological tissue data, and in-vivo clinical data.

View details for DOI 10.1109/TMI.2018.2861570

View details for Web of Science ID 000455110500025

View details for PubMedID 30072317