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The Innate Sense of Bacteriophages.
The Innate Sense of Bacteriophages. Cell host & microbe Bollyky, P. L., Secor, P. R. 2019; 25 (2): 177–79Abstract
Perturbation of the gut microbiota is associated with inflammatory bowel disease, obesity, and even cancer. In this issue of Cell Host & Microbe, Gogokhia et al. 2019 sought to kill cancer-causing bacteria with bacteriophages. However, the bacteriophages themselves directly stimulated an immune response, which worsened inflammatory bowel disease pathogenesis.
View details for PubMedID 30763530