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Optical Coherence Tomography Angiography of RPGR- Associated Retinitis Pigmentosa Suggests Foveal Avascular Zone is a Biomarker for Vision Loss OPHTHALMIC SURGERY LASERS & IMAGING RETINA Tang, P. H., Jauregui, R., Tsang, S. H., Bassuk, A. G., Mahajan, V. B. 2019; 50 (2): E44–E48

Abstract

RPGR-associated retinitis pigmentosa (RP) is a progressive disease with retina degeneration. Optical coherence tomography angiography (OCTA) is an imaging technique that provides novel insights. The authors report two affected male siblings who underwent OCTA imaging. The area of the foveal avascular zone (FAZ) was measured. Although the younger sibling exhibited more advanced clinical disease, his visual acuity was superior to his older sibling. OCTA imaging revealed a better preserved FAZ in the younger sibling as the reason for this. It also highlighted attenuation of choriocapillaris / choroid layers as biomarkers for disease severity. This provides new insights into retinal degeneration in RPGR-associated RP. [Ophthalmic Surg Lasers Imaging Retina. 2019;50:e44-e48.].

View details for DOI 10.3928/23258160-20190129-18

View details for Web of Science ID 000458843200007

View details for PubMedID 30768229