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The impact of concomitant viral pathogens on the course of Pneumocystis carinii pneumonia. journal of protozoology Bozzette, S. A., ARCIA, J., BARTOK, A. E., McGlynn, L. M., McCutchan, J. A., Richman, D. D., Spragg, R., Spector, S. A. 1991; 38 (6): 183S-184S

Abstract

A large retrospective study was conducted to evaluate the impact of culturing cytomegalovirus from the respiratory secretions of AIDS patients with Pneumocystis carinii pneumonia. Pneumocystis carinii was found in 220 (67%) of 327 episodes and cytomegalovirus was found in 106 (48%) of the P. carinii-positive patients. Cytomegalovirus-positive and -negative patients were similar at baseline and had a similar number of hospital days, but had a lower incidence of early deterioration in oxygenation, fewer intensive-care days, were less frequently intubated, and had a higher 30-day survival. The better short-term outcome of cytomegalovirus positive patients observed in this study may relate to the immunosuppressive effects of cytomegalovirus.

View details for PubMedID 1667929