Computed tomography characteristics of the aortic valve and the geometry of SAPIEN 3 transcatheter heart valve in patients with bicuspid aortic valve disease EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING Kawamori, H., Yoon, S., Chakravarty, T., Maeno, Y., Kashif, M., Israr, S., Abramowitz, Y., Mangat, G., Miyasaka, M., Rami, T., Kazuno, Y., Takahashi, N., Jilaihawi, H., Nakamura, M., Cheng, W., Friedman, J., Berman, D., Sharma, R., Makkar, R. R. 2018; 19 (12): 1408–18


We assessed the geometry of transcatheter heart valve (THV) and valve function associated with SAPIEN 3 implantation in patients with bicuspid aortic valve (BAV) stenosis.We included 280 consecutive patients who had a contrast computed tomography (CT) before and after transcatheter aortic valve implantation (TAVI) in our institution. Each THV was assessed by CT at five cross-sectional levels: inflow, annulus, mid, sinus, and outflow. The geometry of THV was assessed for eccentricity (1 - minimum diameter/maximum diameter) and expansion (CT derived external valve area/nominal external valve area). CT measurements and transthoracic echocardiogram data were compared between BAV and tricuspid aortic valve (TAV). Among 280 patients, 41 patients were diagnosed as BAV. Compared to TAV, BAV was associated with lower expansion at mid-level, sinus-level, and outflow-level (mid 94.1?±?6.8% vs. 98.1?±?7.8%; P?=?0.002, sinus 95.9?±?7.2% vs. 101.6?±?8.5%; P?

View details for DOI 10.1093/ehjci/jex333

View details for Web of Science ID 000455360200016

View details for PubMedID 29315371