In vitro antibiotic susceptibility of preoperative normal conjunctival bacteria EYE Ta, C. N., He, L., De Kaspar, H. M. 2009; 23 (3): 559-560

Abstract

To determine the antibiotic susceptibility of preoperative conjunctival bacterial flora.Antibiotic susceptibility of conjunctival bacterial strains isolated from 142 patients undergoing intraocular surgery was determined using the Kirby-Bauer disc diffusion technique. chi(2) statistical analysis was performed.Among the 116 bacteria isolated, 95 (82%) were coagulase-negative staphylococci (CNS). Most (>75%) of them were susceptible to vancomycin, minocycline, aminoglycosides, gatifloxacin, levofloxacin, and moxifloxacin. Approximately one-half of CNS was resistant to erythromycin and azithromycin. Over 90% of streptococci were susceptible to levofloxacin, moxifloxacin, and gatifloxacin.Fluoroquinolones, specifically gatifloxacin, levofloxacin, and moxifloxacin continue to provide broad-spectrum coverage against common conjunctival bacterial flora.

View details for DOI 10.1038/eye.2008.65

View details for Web of Science ID 000264119500010

View details for PubMedID 18356928