Respiratory depression after neuraxial opioids in the obstetric setting ANESTHESIA AND ANALGESIA Carvalho, B. 2008; 107 (3): 956-961


Neuraxial opioids have contributed significantly to improved labor and postcesarean delivery analgesia. In the obstetric population, epidural and intrathecal opioids are associated with a very low risk of clinically significant respiratory depression. Although rare, respiratory depression is a serious risk; patients may die or suffer permanent brain damage as a consequence. This review discusses the mechanism and incidence, as well as the prevention, detection, and management of respiratory depression with morphine, extended-release epidural morphine, and lipophilic opioids in the labor and cesarean delivery setting.

View details for DOI 10.1213/ane.0b013e318168b443

View details for Web of Science ID 000258702500041

View details for PubMedID 18713913