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Normal pregnancy resulting from a non-pronuclear oocyte at the time of examination for fertilization CLINICAL AND EXPERIMENTAL OBSTETRICS & GYNECOLOGY Burney, R. O., Gebhardt, J., Shu, Y., Behr, B., Westphal, L. M. 2008; 35 (3): 170-171

Abstract

To report the case of a patient undergoing in vitro fertilization (IVF) in which a non-pronuclear (0PN) oocyte resulted in a normal pregnancy.A 36-year-old woman underwent an IVF-embryo transfer treatment cycle.Four oocytes were retrieved for insemination by IVF. Examination for fertilization revealed two polypronuclearpolygynic and two non-pronuclear oocytes. The non-pronuclear oocytes were observed further for development. One embryo developed from the non-pronuclear cohort and was transferred at the 8-cell stage on day 3. Subsequently, a pregnancy developed, and resulted in the delivery of a healthy term infant.Non-pronuclear oocytes may represent a source of developmentally competent embryos, and further observation of this cohort should be considered, particularly in situations involving a low yield of oocytes at retrieval.

View details for PubMedID 18754284