Disaggregating Hispanic American cancer mortality burden by detailed ethnicity. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology Zamora, S. M., Pinheiro, P. S., Gomez, S. L., Hastings, K. G., Palaniappan, L. P., Hu, J., Thompson, C. A. 2019

Abstract

Hispanics are the largest minority population in the United States (18%). They represent a heterogeneous and growing population. Cancer is the leading cause of death among Hispanics, yet few studies have described cancer mortality burden by specific Hispanic group nationwide.Cancer-related deaths from U.S. death certificates for the years 2003-2012 were analyzed for decedents identifying as Mexican, Puerto Rican, Cuban, and Central or South American. We calculated descriptive statistics including potential years of lives lost (PYLL), age-adjusted rates, standardized mortality ratios, and fitted JoinPoint regression models to evaluate annual trends by Hispanic group, using non-Hispanic Whites (NHWs) as the reference population.We identified 287,218 cancer deaths among Hispanics and 4,570,559 among NHWs. Mortality trends were heterogeneous across Hispanic groups. Female NHWs and male Puerto Ricans had the greatest rates of adjusted PYLL per 1000 (NHWs, 19.6; Puerto Ricans, 16.5). Liver cancer was ranked among the top 5 cancer-related deaths for every Hispanic group, but not for NHWs. Stomach cancer mortality was twice as high for most Hispanic groups when compared to NHWs and especially high for Mexicans (male SMR, 2.07; 95% CI, 2.01-2.13; female SMR, 2.62; 95% CI, 2.53-2.71) Conclusion: We observed marked heterogeneity in cancer mortality across Hispanic groups. Several cancers affect Hispanics disproportionately compared to NHWs. Screening programs in Hispanics should be considered for stomach and liver cancer.Disaggregated analysis of Hispanics is needed to fully understand cancer burden among the diverse Hispanic population and is critical for cancer prevention and control efforts.

View details for DOI 10.1158/1055-9965.EPI-18-0872

View details for PubMedID 31147314