Breast Cancer Posttreatment Surveillance: Diagnosis and Management of Recurrent Disease CLINICAL OBSTETRICS AND GYNECOLOGY Karam, A. K. 2011; 54 (1): 157–63


Invasive breast cancer is the most common malignancy diagnosed in American women. The use of screening mammography and progress in adjuvant therapy has led to a steady decline in breast cancer mortality, and as the number of breast cancer survivors increases, there has been a marked increase in the number of patients enrolled in posttreatment surveillance programs.The majority of breast cancer recurrences occurs during the first decade after initial diagnosis with a peak incidence 2 to 5 years after diagnosis, although the number of recurrences for endocrine responsive cancer continues to rise afterward. The goal of posttreatment follow-up programs in patients with breast cancer is to detect potentially curable locoregional recurrences, second primary tumors, and the detection of systemic relapses. However, contrary to the long-held belief, most recurrences are symptomatic and occur during the interval between scheduled visits.

View details for DOI 10.1097/GRF.0b013e318208393b

View details for Web of Science ID 000286656300022

View details for PubMedID 21278515