Results of the economic evaluation of the first study - A multinational prospective economic evaluation INTERNATIONAL JOURNAL OF TECHNOLOGY ASSESSMENT IN HEALTH CARE Schulman, K. A., Buxton, M., Glick, H., Sculpher, M., Guzman, G., Kong, J., Backhouse, M., Mauskopf, J., Bell, L., Eisenberg, J. M., Califf, R. M., McKenna, W. J., Harrell, F. E., Uretsky, B. F., Adams, K. F., Swedberg, K. B., Gheorghiade, M., Zannad, F., Handberg, E., Darius, H., SolerSoler, J., Wheeler, W. S., Armstrong, P. W., Patterson, H., Murali, S., Butman, S., Kirlin, P. C., Miller, L. W., Jafri, S., Rich, S., CostanzoNordin, M. R., McGoon, M., Hosenpud, J. D., Ratkovec, R., Brundage, B., Pritzker, M., Bourge, R., Reeves, W., Forgosh, L., Ventura, H., Young, J. B., Mancini, D., Mills, R. M., Limacher, M. C., Lee, F., Revkin, J., Kalbfleisch, J. M., Fishbein, D., Pressler, M., Haeusslein, E., Karlsberg, R. P., OConnell, J., LeJemtel, T. H., Thomas, H. M., Smith, W. B., McIvor, M., Cintron, G. B., Hager, W. D., Messineo, F. C., Dougherty, J. E., Hassapoyannes, C., Hood, W., McGrew, F., Sanford, C. F., OConner, C. M., Hobbs, R. E., Yardley, D., Kay, R., Minotti, J., Eastburn, T. E., Lindenfeld, J., Litman, G., Wickemeyer, W., Horton, S., Gilbert, E. M., Eichorn, E., Ribner, H. S., Corder, C., Philbin, E., Nocero, M., Elkayam, U., Jessup, M., Crawford, M., Carson, P., Reddy, H. K., Klapholz, M., Heywood, J. T., Salinger, M., Karlsberg, R., Bush, D., Hunter, C., Wohns, D., Eisenberg, P., Winston, S., Butcher, C., Massin, E., Wynne, J., Tonkon, M., Spaccavento, L., Diver, D., Ghali, J., Hutchins, S., Anand, Beanlands, D., Kostuk, W., Pflugfelder, P., Langleben, D., Latour, P., Mizgala, H., Ricci, D., Manyari, D., Dargie, H. J., Davidson, C., Swanton, H., Hubner, P. J., Oakley, D., Brooks, N., Jennings, K., Greenbaum, R. A., Penny, W. J., Nicholls, P., Walsh, M., Sugrue, D., Fennell, W., Horgan, J. H., Jondeau, G., Castaigne, A., LeMarec, H., Walger, P., Park, J. W., deBerrazueta, Mol, M. G., Sanchez, M. A., Caponnetto, S., Magnani, B., Galie, N., DeVita, C., Maseri, A., Bagger, J. P., Remes, J., Waldenstrom, A., Schaufelberger, M., Diensti, F., Simoons, M. L., Klein, W., Pacher, R., Keogh, A., Harley, A. 1996; 12 (4): 698–713

Abstract

We present the prospective economic evaluation that served as a secondary endpoint for the FIRST study, a randomized international multicenter trial of patients with severe congestive heart failure. Although the clinical results of this study were disappointing, we demonstrated the feasibility of incorporating prospective economic evaluation in phase III clinical trials.

View details for DOI 10.1017/S0266462300010989

View details for Web of Science ID A1996WE15000012

View details for PubMedID 9136477