Generating evidence for therapeutic effects: the need for well-conducted randomized trials. The Journal of clinical investigation Califf, R. M., Curtis, L. H., Harrington, R. A., Hernandez, A. F., Peterson, E. D. 2020

Abstract

In this viewpoint, Robert Califf, former commissioner of the U.S. Food and Drug Administration, and colleagues reflect on how to approach questions about which patient treatments and strategies work, particularly in light of the tremendous pressure on the government and biomedical research enterprise to quickly develop safe, effective therapies during the SARS-CoV-2 pandemic.

View details for DOI 10.1172/JCI146391

View details for PubMedID 33270604