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Sinonasal adenocarcinoma: A population-based analysis of demographic and socioeconomic disparities.

Sinonasal adenocarcinoma: A population-based analysis of demographic and socioeconomic disparities. Head & neck Low, C. M., Balakrishnan, K., Smith, B. M., Stokken, J. K., O'Brien, E. K., Van Gompel, J. J., Rowan, N. R., Choby, G. 2021

Abstract

BACKGROUND: Sinonasal adenocarcinoma (SNAC) is a rare tumor. The impact of health disparities on survival, stage at presentation, and utilization of surgery is not well understood in patients with SNAC.METHODS: The Surveillance, Epidemiology, and End Results database was queried for cases of SNAC from 1973 to 2015. Cases were analyzed to assess for disparities in presentation, treatment, and survival.RESULTS: SNAC was identified in 630 patients. In a multivariate model of overall survival, an age increase of 10years (Hazard Ratio (HR)=1.37, p<0.001), male sex (HR=1.26, p=0.045), and more recent decade of diagnosis (HR=0.74, p<0.001) were significantly related to time-to-death. There is a higher rate of SNAC-related death in counties with more rural populations (p=0.027).CONCLUSION: Future interventions targeting rural and less well-educated populations may improve care with the goal of increasing the span of healthy life and reducing survival disparities related to SNAC.

View details for DOI 10.1002/hed.26783

View details for PubMedID 34117674