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Abstract
Data from mouse models and from human cancers have supported the idea that telomere shortening leads to chromosomal instability and epithelial carcinogenesis. In this issue of Cancer Cell, Else et al. demonstrate that telomere uncapping-altering a protein that protects chromosome ends without shortening telomeres-also results in epithelial cancers.
View details for DOI 10.1016/j.ccr.2009.05.006
View details for Web of Science ID 000266686500001
View details for PubMedID 19477422