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Efficacy of Etanercept in the Treatment of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis. Cutis Dreyer, S. D., Torres, J., Stoddard, M., Leavitt, E., Sutton, A., Aleshin, M., Crew, A., Worswick, S. 2021; 107 (6): E22-E28

Abstract

It has been suggested that the use of etanercept for treatment of Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) might provide improved mortality benefit and decreased skin healing times. This retrospective study compared the use of single-dose subcutaneous etanercept to intravenous immunoglobulin (IVIG) and supportive care alone. Thirteen patients were treated with a single dose (50 mg) of subcutaneous etanercept. Results of this study support the use of etanercept as a potentially beneficial agent in the treatment of SJS/TEN.

View details for DOI 10.12788/cutis.0288

View details for PubMedID 34314327