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Two Photon Fluorescence Microscopy of the Unstained Human Cochlea Reveals Organ of Corti Cytoarchitecture
Two Photon Fluorescence Microscopy of the Unstained Human Cochlea Reveals Organ of Corti Cytoarchitecture FRONTIERS IN CELLULAR NEUROSCIENCE Iyer, J. S., Seist, R., Moon, I., Stankovic, K. M. 2021; 15: 690953Abstract
Sensorineural hearing loss (SNHL) is the most common sensory deficit worldwide, and it typically originates from the cochlea. Methods to visualize intracochlear cells in living people are currently lacking, limiting not only diagnostics but also therapies for SNHL. Two-photon fluorescence microscopy (TPFM) is a high-resolution optical imaging technique. Here we demonstrate that TPFM enables visualization of sensory cells and auditory nerve fibers in an unstained, non-decalcified adult human cochlea.
View details for DOI 10.3389/fncel.2021.690953
View details for Web of Science ID 000684747300004
View details for PubMedID 34421541
View details for PubMedCentralID PMC8376148