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Development of the Alopecia Areata Scale for Clinical Use: Results of an Academic-Industry Collaborative Effort. Journal of the American Academy of Dermatology King, B. A., Mesinkovska, N. A., Craiglow, B., Kindred, C., Ko, J., McMichael, A., Shapiro, J., Goh, C., Mirmirani, P., Tosti, A., Hordinsky, M., Huang, K. P., Castelo-Soccio, L., Bergfeld, W., Paller, A. S., Mackay-Wiggan, J., Glashofer, M., Aguh, C., Piliang, M., Yazdan, P., Lo Sicco, K., Cassella, J. V., Koenigsberg, J., Ahluwalia, G., Ghorayeb, E., Fakharzadeh, S., Napatalung, L., Gandhi, K., DeLozier, A. M., Nunes, F. P., Senna, M. M. 2021

Abstract

BACKGROUND: The current classification for Alopecia Areata (AA) does not provide a consistent assessment of disease severity.OBJECTIVE: To develop an AA severity scale based on expert experience.METHODS: A Modified Delphi process was utilized. An advisory group of 22 US-based AA clinical experts was formed to develop this AA scale. Representatives from the pharmaceutical industry provided feedback during its development.RESULTS: Survey responses were used to draft severity criteria, aspiring to develop a simple scale that may be easily applied in clinical practice. A consensus vote was held to determine the final AA severity statement, with all AA experts agreeing with the adoption of the proposed scale.LIMITATIONS: The scale is a static assessment intended to be used in clinical practice, and not clinical trials.CONCLUSIONS: The final AA disease severity scale, anchored on extent of hair loss, captures key features commonly used by AA experts in clinical practice. This scale will better aid clinicians in appropriately assessing severity in patients with this common disease.

View details for DOI 10.1016/j.jaad.2021.08.043

View details for PubMedID 34474079