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Stem Cell Aging and Aberrant Differentiation within the Niche CELL STEM CELL Choi, J., Artandi, S. 2009; 5 (1): 6-8

Abstract

Stem cells age, but the underlying mechanisms remain unclear. In a recent issue of Cell, Inomata and colleagues (2009) show that DNA damage, a prime suspect in stem cell aging, causes graying and loss of melanocyte stem cells by inducing premature differentiation, without inducing apoptosis or senescence.

View details for DOI 10.1016/j.stem.2009.06.006

View details for Web of Science ID 000267879200004

View details for PubMedID 19570507