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Living donor liver transplantation for hepatoblastoma with Beckwith-Wiedemann syndrome PEDIATRIC TRANSPLANTATION Sasaki, K., Kasahara, M., Fukuda, A., Shigeta, T., Tanaka, H., Nakagawa, S., Mitsui, K., Harada, R., Nakagawa, A. 2010; 14 (7): E89-E92

Abstract

BWS is one of the most well-known somatic overgrowth syndromes, which is characterized by macroglossia, organomegaly, abdominal wall defects, and predisposition to embryonal tumors, such as Wilms' tumor, hepatoblastoma, and adrenocortical carcinoma. We report a case of BWS in a girl with unresectable hepatoblastoma, who received a planned LVDT following neo-adjuvant chemotherapy. This is the first case report of liver transplantation for patients with BWS. Tumor surveillance after transplantation would be necessary to detect possible recurrence of the original disease and development of other malignancies.

View details for DOI 10.1111/j.1399-3046.2009.01198.x

View details for Web of Science ID 000283067800003

View details for PubMedID 19496980