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Coronary volume to left ventricular mass ratio in patients with diabetes mellitus.
Coronary volume to left ventricular mass ratio in patients with diabetes mellitus. Journal of cardiovascular computed tomography Kuneman, J. H., El Mahdiui, M., van Rosendael, A. R., van den Hoogen, I. J., Patel, M. R., Norgaard, B. L., Fairbairn, T. A., Nieman, K., Akasaka, T., Berman, D. S., Hurwitz Koweek, L. M., Pontone, G., Kawasaki, T., Ronnow Sand, N. P., Jensen, J. M., Amano, T., Poon, M., Ovrehus, K. A., Sonck, J., Rabbat, M. G., De Bruyne, B., Rogers, C., Matsuo, H., Bax, J. J., Leipsic, J. A., Knuuti, J. 2022Abstract
BACKGROUND: Diabetes mellitus is a major risk factor for coronary artery disease (CAD) and may provoke structural and functional changes in coronary vasculature. The coronary volume to left ventricular mass (V/M) ratio is a new anatomical parameter capable of revealing a potential physiological imbalance between coronary vasculature and myocardial mass. The aim of this study was to examine the V/M derived from coronary computed tomography angiography (CCTA) in patients with diabetes.METHODS: Patients with clinically suspected CAD enrolled in the ADVANCE (Assessing Diagnostic Value of Non-invasive FFRCT in Coronary Care) registry and known diabetic status were included. Coronary artery volume and left ventricular myocardial mass were analyzed from CCTA and the V/M ratio was calculated and compared between patients with and without diabetes.RESULTS: Of the 3053 patients (age 66?±?10 years; 66% male) with known diabetic status, diabetes was present in 21.9%. Coronary volume was lower in patients with diabetes compared to those without diabetes (2850?±?940?mm3 vs. 3040?±?970?mm3, p?
View details for DOI 10.1016/j.jcct.2022.01.004
View details for PubMedID 35190274