New to MyHealth?
Manage Your Care From Anywhere.
Access your health information from any device with MyHealth. You can message your clinic, view lab results, schedule an appointment, and pay your bill.
ALREADY HAVE AN ACCESS CODE?
DON'T HAVE AN ACCESS CODE?
NEED MORE DETAILS?
MyHealth for Mobile
Extraskeletal myxoid chondrosarcoma: Clinicopathological features and outcomes from the United States sarcoma collaborative database.
Extraskeletal myxoid chondrosarcoma: Clinicopathological features and outcomes from the United States sarcoma collaborative database. Journal of surgical oncology Gusho, C. A., King, D., Ethun, C. G., Cardona, K., Harrison Howard, J., Tran, T. B., Poultsides, G., Tseng, J., Roggin, K. K., Fields, R. C., Cullinan, D. R., Chouliaras, K., Votanopoulos, K., Grignol, V. P., Bedi, M. 2022Abstract
BACKGROUNDS AND OBJECTIVES: This investigation described clinicopathological features and outcomes of extraskeletal myxoid chondrosarcoma (EMC) patients.METHODS: EMC patients were identified from the United States Sarcoma Collaborative database between 2000 and 2016. Overall survival (OS) and recurrence-free survival (RFS) were calculated, and prognostic factors were analyzed.RESULTS: Sixty individuals with a mean age of 55 years were included, and 65.0% (n=39) were male. 73.3% (n=44) had a primary tumor. A total of 41.6% (n=25) developed tumor relapse following resection. The locoregional recurrence rate was 30.0% (n=18/60), and mean follow-up was 42.7 months. The 5-year OS was 71.0%, while the 5-year RFS was 41.4%. On multivariate analysis for all EMC, chemotherapy (hazard ratio[HR], 6.054; 95% confidence interval [CI], 1.33-27.7; p=0.020) and radiation (HR, 5.07, 95% CI, 1.3-20.1; p=0.021) were independently predictive of a worse RFS. Among patients with primary EMC only, the 5-year OS was 85.3%, with a 30.0% (n=12) locoregional recurrence rate, though no significant prognostic factors were identified.CONCLUSIONS: Long-term survival with EMC is probable, however there exists a high incidence of locoregional recurrence. While chemotherapy and radiation were associated with a worse RFS, these findings were likely confounded by recurrent disease as significance was lost in the primary EMC-only subset.
View details for DOI 10.1002/jso.27062
View details for PubMedID 35962783