New to MyHealth?
Manage Your Care From Anywhere.
Access your health information from any device with MyHealth. You can message your clinic, view lab results, schedule an appointment, and pay your bill.
ALREADY HAVE AN ACCESS CODE?
DON'T HAVE AN ACCESS CODE?
NEED MORE DETAILS?
MyHealth for Mobile
Health-related quality of life in acute heart failure: Association between patient-reported symptoms and markers of congestion.
Health-related quality of life in acute heart failure: Association between patient-reported symptoms and markers of congestion. European journal of heart failure Lee, M. M., Campbell, R. T., Claggett, B. L., Lewis, E. F., Docherty, K. F., Lindner, M., Liu, J., Solomon, S. D., McMurray, J. J., Platz, E. 2022Abstract
AIMS: The aim of this study was to examine the association between patient-reported symptoms and the extent of pulmonary congestion in acute heart failure (AHF).METHODS AND RESULTS: In this prospective, observational study, patient-reported symptoms were assessed at baseline using the Kansas City Cardiomyopathy Questionnaire Total Symptom Score (KCCQ-TSS) (range 0-100; 0 worst) in patients hospitalized for AHF. In a subset, patient-reported dyspnea at rest and on exertion was examined (range 0-10; 10 worst) at baseline. In addition, 4-zone lung ultrasound (LUS) was performed at baseline at the time of echocardiography. B-lines were quantified offline, blinded to clinical findings, in a core laboratory. Chest x-ray (CXR) and physical examination findings were collected from the medical records. Among 322 patients (mean age 72, 60% men, mean LVEF 39%) with AHF, the median KCCQ-TSS score was 33 [interquartile range 18-48]. Worse KCCQ-TSS was associated with worse NYHA class, dyspnea at rest and on exertion, and peripheral edema (p trend <0.001 for all). However, KCCQ-TSS was not associated with the extent of pulmonary congestion, as assessed by the number of B-lines on LUS, or findings on CXR or physical examination (p trend >0.30 for all). Similarly, KCCQ-TSS was not significantly associated with echocardiographic markers of left ventricular filling pressure, pulmonary pressure or with NT-proBNP.CONCLUSIONS: Among patients hospitalized for AHF, at baseline, KCCQ-TSS was not associated with pulmonary congestion assessed by LUS, CXR or physical examination. These findings suggest that the profound reduction in KCCQ-TSS in patients with AHF may not be solely explained by pulmonary congestion. This article is protected by copyright. All rights reserved.
View details for DOI 10.1002/ejhf.2699
View details for PubMedID 36161429