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Human intracranial high-frequency activity during memory processing: neural oscillations or stochastic volatility? Current opinion in neurobiology Burke, J. F., Ramayya, A. G., Kahana, M. J. 2015; 31: 104-10

Abstract

Intracranial high-frequency activity (HFA), which refers to fast fluctuations in electrophysiological recordings, increases during memory processing. Two views have emerged to explain this effect: (1) HFA reflects a synchronous signal, related to underlying gamma oscillations, that plays a mechanistic role in human memory and (2) HFA reflects an asynchronous signal that is a non-specific marker of brain activation. We review recent data supporting each of these views and conclude that HFA during memory processing is more consistent with an asynchronous signal. Memory-related HFA is therefore best conceptualized as a biomarker of neural activation that can functionally map memory with high spatial and temporal precision.

View details for DOI 10.1016/j.conb.2014.09.003

View details for PubMedID 25279772

View details for PubMedCentralID PMC4675136