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Extrinsic Outflow Graft Obstruction of the HeartMate 3 LVAD: A State-of-the-Art Review.

Extrinsic Outflow Graft Obstruction of the HeartMate 3 LVAD: A State-of-the-Art Review. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation Goldstein, D. J., Kanwar, M., Cowger, J., Patel, S., Meyer, D. M., Molina, E., Salerno, C., Elmer, A., Schettle, S., Teuteberg, J., Pagani, F., Stehlik, J. 2024

Abstract

While notable improvements in survival, incidence of hemocompatibility-related adverse events, hospitalizations and cost have been demonstrated with the only commercially available durable left ventricular assist device, a category of pump malfunctions characterized by outflow graft obstruction has been noted with broader use and clinical follow up of recipients of this technology. Of particular concern, is the accumulation of acellular biodebris between the outflow graft and bend relief covering the outflow graft at its origin with the pump (which we term extrinsic outflow graft obstruction at the bend relief, or EOGO-BR). This process tends to be insidious, occurs late in the postoperative course, can be challenging to diagnose, and can result in significant morbidity and mortality. Herein we provide a review of this complication and outline diagnostic, treatment and preventive strategies.

View details for DOI 10.1016/j.healun.2024.07.005

View details for PubMedID 39019352