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Transdiagnostic Examination of Interrelationships Between Anxiety, Insistence on Sameness and Compulsions.

Transdiagnostic Examination of Interrelationships Between Anxiety, Insistence on Sameness and Compulsions. Autism research : official journal of the International Society for Autism Research Spackman, E., Chetcuti, L., Baker, E. K., Ferguson, E. F., Yerys, B. E., Herrington, J. D., Frazier, T. W., Leekam, S. R., Hardan, A. Y., Harrington, J. W., Uljarevic, M. 2025

Abstract

Although insistence on sameness (IS) and compulsions occur across a wide range of neurodevelopmental (NDD) and neuropsychiatric (NPD) conditions, they are typically only examined within the confines of specific singular disorders. Indeed, while anxiety has been consistently linked to IS in autism and compulsions in obsessive-compulsive disorder (OCD), no empirical study has examined these associations in a sample spanning a range of NDD and NPD. Therefore, this study utilized a large sample of children and adolescents spanning several NDD and NPD to examine whether anxiety shows different patterns of association with IS or compulsions within and across diagnostic groups. The transdiagnostic sample encompassed youth (mean age?=?10.36 [3.40]; N?=?1852) diagnosed with autism (N?=?387), attention-deficit hyperactivity disorder (ADHD; N?=?931), internalizing disorders (N?=?208), OCD/Tic disorder (N?=?59) and oppositional defiant/conduct disorder (ODD/CD; N?=?267). IS and compulsions were assessed using the Repetitive Behavior Scale-Revised, and anxiety using the Screen for Child Anxiety Related Disorders. Within-group comparisons revealed that, in the autism, ADHD, and OCD/Tic groups, anxiety showed a slightly stronger association with IS than compulsions although effect sizes indicated small to no effect (q?

View details for DOI 10.1002/aur.70096

View details for PubMedID 40878890