Basic Science Review on Adipose Tissue for Clinicians PLASTIC AND RECONSTRUCTIVE SURGERY Brown, S. A., Levi, B., Lequex, C., Wong, V. W., Mojallal, A., Longaker, M. T. 2010; 126 (6): 1936-1946


The recognition that fat contains stem cells has driven further examination into the potential uses of fat and adipose-derived stem cells in a wide number of clinical situations. New information about the harvesting, isolation, and subsequent differentiation properties of isolated adipose-derived stem cells has led to new research into novel tissue-engineered constructs and the transformation of adipose-derived stem cells to induced pluripotent stem cells. Clinically, use of fat grafts and adipose-derived stem cells worldwide and in the United States has dramatically increased in parallel to questions concerning the safety and efficacy of adipose-derived stem cell-based treatments. Currently, the U.S. Food and Drug Administration has not approved the use of isolated adipose-derived stem cells for medical indications.

View details for DOI 10.1097/PRS.0b013e3181f44790

View details for Web of Science ID 000284832400038

View details for PubMedID 21124133