A High Resolution Pharmacokinetic/Pharmacodynamic Model of Propofol in Morbidly Obese Subjects
Trial ID or NCT#
NCT01591148
Status
NOT RECRUITING
Purpose
This study will determine how morbid obesity affects the distribution and metabolism of the drug propofol. The investigators hypothesize that propofol will be distributed and metabolized differently in morbidly obese subjects as compared to normal weight subjects.
Official Title
A High Resolution Pharmacokinetic/Pharmacodynamic Model of Propofol in Morbidly Obese Subjects
Eligibility Criteria
Ages Eligible for Study: 18 Years to 70 Years
Sexes Eligible for Study: All
Accepts Healthy Volunteers: No
Inclusion Criteria:
- - adult age (ages 18-70) - body mass index greater than 40 or between 20-25 - American Society of Anesthesiologists Class I, II, or III - undergoing elective surgical procedure requiring general anesthesia
Exclusion Criteria:
- - evidence of cardiovascular or pulmonary disease - kidney or liver dysfunction - drug allergy to propofol - history of difficult airway - on prescribed or over the counter anxiolytics, antipsychotics, or sleeping aids - unable to speak or understand English
Contact us to find out if this trial is right for you.
Contact
Jerry Ingrande, M.D., M.S.
650-723-7377
View on ClinicalTrials.gov
