A Pilot Study of Vitamin D in Boys With X-linked Adrenoleukodystrophy
Trial ID or NCT#
NCT02595489
Status
NOT RECRUITING
Purpose
In this pilot study, the investigators will assess the safety of two high-dose regimens of oral vitamin D supplementation and measure the effects of vitamin D supplementation on markers of oxidative stress and inflammation in the blood and brain of study participants before, during, and after taking vitamin D supplements. The goal of the study is to establish research measures (i.e. biomarkers) and an optimal dose for vitamin D supplementation in boys with the X-linked adrenoleukodystrophy (ALD) genotype.
Official Title
A Pilot Study of Vitamin D in Boys With X-linked Adrenoleukodystrophy
Eligibility Criteria
Ages Eligible for Study: 18 Months to 25 Years
Sexes Eligible for Study: MALE
Accepts Healthy Volunteers: No
Exclusion Criteria:
- * history of liver or kidney disease* history of nephrolithiasis* history of hyperthyroidism* history of ulcerative colitis, Crohn's disease, celiac disease* taking medication interfering with gastrointestinal absorption* contraindication or inability to complete MRI every 6 months
Investigator(s)
Keith Van Haren, MD
Contact us to find out if this trial is right for you.
Contact
Keith Van Haren, MD
View on ClinicalTrials.gov
