Breath Metabolomics in the Laboring Parturient

Trial ID or NCT#

NCT04564196

Status

not recruiting iconNOT RECRUITING

Purpose

This is primarily a feasibility study to determine whether quantitative measurement of volatile organic compounds (VOCs) in the breath of parturients undergoing labor is possible. Aim A: To determine baseline values of breath metabolites and volatile organic compounds (VOCs) in the breath for term pregnant women. Aim B: To gather preliminary data to determine breath metabolite and volatile organic compound (VOCs) signature change during labor and delivery. Aim C: Compare the breath metabolite and volatile organic compound (VOCs) signature women undergoing induction compared to spontaneous vaginal deliveries.

Official Title

Feasibility Study of the Collection of the Breath Metabolome From Healthy Parturients During Labor

Eligibility Criteria

Ages Eligible for Study: Older than 18 Years
Sexes Eligible for Study: FEMALE
Accepts Healthy Volunteers: No
Inclusion Criteria:
  1. * Otherwise healthy nulliparous women with singleton term (37-41 weeks) pregnant at least 18 years of age.* Presenting for labor (induction of labor and spontaneous labor) at LPHC.
Exclusion Criteria:
  1. * Participants unable to or refuse to give informed consent* Participants that do not understand English or are hearing impaired* Medical History: Chronic disease (HTN, diabetes, asthma)* Obstetric History during this pregnancy: gestational diabetes, gestational hypertension, pre-eclampsia, Eclampsia* Multiple gestation* Any significant fetal anomalies* Morbid obesity (BMI\>50)
View All Criteria
Show Less

Investigator(s)

Cedar Fowler
Clinical Assistant Professor, Anesthesiology, Perioperative and Pain Medicine
Pervez Sultan
Anesthesiologist
Professor of Anesthesiology, Perioperative and Pain Medicine (Obstetrics)

View on ClinicalTrials.gov