Characterization of Treatment Responses in Lymphedema
Trial ID or NCT#
NCT03783715
Status
NOT RECRUITING
Purpose
This study is designed to investigate the treatment response of lymphedema, of the upper or lower extremity, during clinical, pharmacologic treatment of lymphedema with oral ketoprofen. Correlation of clinical responses (changes in limb volume and skin thickness) with changes in the inflammasome will help to define the molecular substrate of treatment response.
Official Title
Characterization of Treatment Responses in Lymphedema
Eligibility Criteria
Ages Eligible for Study: 18 Years to 75 Years
Sexes Eligible for Study: All
Accepts Healthy Volunteers: No
Inclusion Criteria:
- - Participants with a history of acquired lymphedema - Stage 1, 2, or 3 - 18-75 years - Clinical use of ketoprofen for lymphedema
Exclusion Criteria:
- - Active cancer, infection, bleeding tendency, inflammatory disease and/or taking anti-inflammatory or anti-leukotriene medication will be excluded. - Pregnant or lactating females - Inability to take ketoprofen (contra-indicated, e.g patients with known CV, GI, renal, hepatic disease). - Other severe acute or chronic medical or psychiatric condition or laboratory abnormality that may increase the risk associated with study participation, may interfere with interpretation of study results, and in the judgement of the investigator, would make the participation inappropriate for entry into this study.
Investigator(s)
Stanley G. Rockson, MD
Cardiologist
Allan and Tina Neill Professor of Lymphatic Research and Medicine
Contact us to find out if this trial is right for you.
Contact
Leslie Roche, RN
650-723-1396
View on ClinicalTrials.gov
