Composite Health Assessment Risk Model (CHARM) for Older Adults (BMT CTN 1704)

Trial ID or NCT#

NCT03992352

Status

not recruiting iconNOT RECRUITING

Purpose

Prospective observational multicenter study of allogeneic Hematopoietic Stem Cell Transplantation (HCT) in recipients 60 years and older to assess important determinants of health status to be combined into a composite health risk model to improve risk assessment of non-relapse mortality (NRM).

Official Title

Composite Health Assessment Risk Model (CHARM) for Older Adults: Applying Pre-Transplant Comorbidity, Geriatric Assessment, and BioMarkers on Non-Relapse Mortality After Allogeneic Transplant (BMT CTN 1704)

Eligibility Criteria

Ages Eligible for Study: Older than 60 Years
Sexes Eligible for Study: All
Accepts Healthy Volunteers: No
Inclusion Criteria:
  1. 1. Subject is > 60.0 years old at time of enrollment. 2. Hematological malignancy as an indication for allogeneic transplantation. 3. Eligible for allogeneic transplantation based on institutional standards 4. First allogeneic transplant planned. Any conditioning regimen and allogeneic donor is acceptable. 5. Able to speak and read English. Spanish, and Mandarin will be acceptable when sites have ability to perform healthcare provider tests in those languages. 6. Written informed consent
Exclusion Criteria:
  1. 1. Prior allogeneic HCT
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Investigator(s)

Laura Johnston
Laura Johnston
Blood and marrow transplant specialist, Blood and marrow transplant specialist, Medical oncologist, Hematologist
Professor of Medicine (Blood and Marrow Transplantation and Cellular Therapy)

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Contact

Melanie Gaudinez
650-725-4983

View on ClinicalTrials.gov