Comparing Diuretic Strategies in Hospitalized Heart Failure

Trial ID or NCT#

NCT03999216

Status

not recruiting iconNOT RECRUITING

Purpose

We will conduct a pragmatic randomized trial comparing whether using a combination of two types of diuretics (loop + thiazide) compared with using a single diuretic (loop only) will result in shorter hospital stays for patients hospitalized with heart failure.

Official Title

Creating a Platform for Point-of-Care Pragmatic Clinical Trials: Comparing Diuretic Strategies in Heart Failure

Eligibility Criteria

Ages Eligible for Study: Older than 18 Years
Sexes Eligible for Study: All
Accepts Healthy Volunteers: No
Inclusion Criteria:
  1. Any adult (age ≥18 years) admitted to the Heart Failure Service at Stanford Health Care with an indication for treatment with a diuretic.
Exclusion Criteria:
  1. 1. admission to the intensive care unit or cardiac care units 2. maintenance dialysis on admission 3. any mechanical circulatory support on admission 4. history of heart transplant 5. allergy / intolerance to loop or thiazide diuretics 6. admission serum sodium < 125 meq/L (from EPIC) 7. admission serum potassium < 3.0 meq/L (from EPIC)
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Investigator(s)

Tara I. Chang
Tara I. Chang
Nephrologist - Kidney specialist, Refractory hypertension specialist, Heart and kidney disease specialist, Nephrologist
Stanford University Professor of Nephrology

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Contact

Tara Chang, MD, MS

View on ClinicalTrials.gov