CD22-CAR T Cells in Children and Young Adults With B Cell Malignancies

Trial ID or NCT#

NCT04088864

Status

not recruiting iconNOT RECRUITING

Purpose

The primary purpose of this study is to test whether CD22-CAR T cells can be successfully made from immune cells collected from pediatric and young adult subjects with relapsed/refractory B-cell malignancies (leukemia and lymphoma). Another purpose of this study is to test the safety and cancer killing ability of a cell therapy against a new cancer target (CD22).

Official Title

Phase Ib Clinical Trial of Autologous CD22 Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory B Cell Malignancies

Eligibility Criteria

Ages Eligible for Study: 1 Year to 30 Years
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers: No
Exclusion Criteria:

Investigator(s)

Crystal Mackall
Sneha Ramakrishna

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Contact

Amy Li
650-725-4318