Desflurane or Propofol Anesthesia in Elderly Obese Patients Undergoing Total Knee Replacement

Trial ID or NCT#

NCT01270620

Status

recruiting iconRECRUITING

Purpose

You are invited to participate in a research study assessing your mental status in the first days after your surgery and how you will be doing in the 2 years following the surgery. The investigators hope to learn more about the incidence of postoperative confusion and a possible relation with 2 anesthesia techniques that are routinely used. The first one is an anesthesia technique that uses the inhaled anesthetic gas desflurane and the second one is an anesthesia technique that uses the anesthetic propofol administered by infusion in a vein. The investigators are also looking to see if there is a relationship between anesthesia technique and cardiovascular outcomes. You were selected as a possible participant in this study because at your age this phenomenon appears to have a greater incidence.

Official Title

Desflurane or Propofol Anesthesia in Elderly Obese Patients Undergoing Total Knee Replacement: A Pilot Assessment of Short-term and Long-term Differences in Outcome

Eligibility Criteria

Ages Eligible for Study: Older than 65 Years
Sexes Eligible for Study: All
Accepts Healthy Volunteers: No
Inclusion Criteria:
  1. - Age > 65 years old - Body mass index > 30 kg/m2 - Undergoing primary total knee arthroplasty surgery - American society of anesthesiology classification II-III
Exclusion Criteria:
  1. - Patient refusal to participate in the study - Patient refusal or failure of regional block - Patients with preexisting neuro-cognitive disorders - Known intolerance to any of the drugs to be used according to the study protocol

Investigator(s)

Hendrikus Lemmens
Hendrikus Lemmens
Anesthesiologist
Professor of Anesthesiology, Perioperative and Pain Medicine

Contact us to find out if this trial is right for you.

Contact

Pedro Tanaka
650-723-6412