Extended Treatment for Smoking Cessation
Trial ID or NCT#
Status
Purpose
Adult smokers (21-65) and adolescent smokers (18 - 21) years of age residing in Alameda and Santa Clara counties will serve as the target population for this study. A total of 400 smokers meeting eligibility criteria will be randomized. Treatment will include both open label and extended treatment phases. Randomization. Participants will be randomized to extended therapy or control conditions at baseline (prior to open label treatment) and the analysis will be intention-to-treat (ITT) to avoid the threat of selection bias. Primary hypothesis. Smokers randomized to receive CBT during extended treatment will have a higher prolonged abstinence rate (PA) at 52 week and 104 week follow-up than participants in the Supportive therapy Control treatment.
Official Title
Extended Treatment for Smoking Cessation
Eligibility Criteria
- * Age at least 18 years at the beginning of the study Smoking at least 10 cigarettes a day (1/2 pack)
- 1. Currently pregnant2. Currently breastfeeding3. Currently diagnosed with a seizure disorder, major depression, liver disease, kidney disease, congestive heart failure or diabetes mellitus4. History of a seizure, seizure disorder, significant head trauma or central nervous system tumor5. Family history of seizures6. Currently using intravenous drugs7. Currently using any drugs (marijuana, alcohol, cocaine, opiates, stimulants, etc.) on a daily basis8. Currently using any over-the-counter stimulants and anorectics (diet pills)9. Currently on bupropion (Wellbutrin, Wellbutrin SR) or other antidepressants, monoamine oxidase inhibitors, antipsychotics, benzodiazepines, theophylline, systemic steroids or levodopa10. Currently on NRT or bupropion (Zyban)11. Current or past diagnosis of anorexia nervosa or bulimia nervosa12. Previous allergic response to bupropion or NRT
Investigator(s)
Contact us to find out if this trial is right for you.
Contact
Erin Crew, M.P.H.
(408) 415-7301
View on ClinicalTrials.gov