Emollient Therapy for Premature Infants in Zimbabwe

Trial ID or NCT#

NCT05461404

Status

not recruiting iconNOT RECRUITING

Purpose

The purpose of this study is to assess the efficacy of topical emollient treatments in improving neonatal growth and mortality rates.

Official Title

Emollient Therapy for Improved Survival and Growth of Very Low Birth Weight Infants in Zimbabwe

Eligibility Criteria

Ages Eligible for Study: Younger than 28 Days
Sexes Eligible for Study: All
Accepts Healthy Volunteers: Yes
Inclusion Criteria:
  1. - infants <72 hours of age - weigh 700-1500 at birth - hospitalized at SMCH
Exclusion Criteria:
  1. - infants who are moribund and highly likely not to survive despite any intervention - significant breaches in their skin barrier - conditions indicating failure to gain weight - critically ill (definition below): 1. Oxygen saturation <88% on oxygen therapy AND ≥2 of the following conditions: 2. respiratory rate <20 or >100 breaths per minute 3. apnea requiring bag-mask ventilation 4. heart rate <100 or >200 beats per minute - congenital syphilis - hydrops fetalis - a life-threatening congenital anomaly or major surgical condition requiring intervention - generalized skin disease or a structural defect involving >5% body surface area likely to produce a defect in epidermal barrier function

Investigator(s)

Gary Darmstadt

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Contact

Gary Darmstadt, MD, MS
650-724-6014