Intraoperative Ketamine Versus Saline in Depressed Patients Undergoing Anesthesia for Non-cardiac Surgery

Trial ID or NCT#

NCT03861988

Status

not recruiting iconNOT RECRUITING

Purpose

This study evaluates whether ketamine, given as part of an anesthetic, improves depression symptoms in depressed patients undergoing non-cardiac surgery. Half of participants will receive a ketamine infusion during surgery, while the other half will receive a placebo (normal saline) during surgery.

Official Title

Double-blind Trial of Intraoperative Ketamine Versus Saline in Depressed Patients Undergoing Anesthesia for Non-cardiac Surgery

Eligibility Criteria

Ages Eligible for Study: 18 Years to 80 Years
Sexes Eligible for Study: All
Accepts Healthy Volunteers: No
Inclusion Criteria:
  1. - Patient presenting for non-cardiac, non-intracranial surgery - Major Depressive Disorder
Exclusion Criteria:
  1. - Pregnant of breastfeeding women
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Investigator(s)

Boris Heifets
Boris Heifets
Anesthesiologist, Neuroanesthesiologist
Assistant Professor of Anesthesiology, Perioperative and Pain Medicine (Adult MSD)

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Contact

Boris D Heifets, MD, PhD
917-620-4241

View on ClinicalTrials.gov