Janus Kinase Inhibition to Prevent Ventilator-induced Diaphragm Dysfunction

Trial ID or NCT#

NCT03681275

Status

recruiting iconRECRUITING

Purpose

We intend, with this study, to prove that blocking the molecular mechanisms whose blockade prevents VIDD in animals, will indeed prevent the development of VIDD in humans as well. We believe that this evidence will serve as the required basis for proceeding with large, ICU-based clinical trial(s) of a drug to prevent VIDD.

Official Title

A Clinical Trial of JAK Inhibition to Prevent Ventilator-induced Diaphragm Dysfunction

Eligibility Criteria

Sexes Eligible for Study: ALL
Accepts Healthy Volunteers: No
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Investigator(s)

Joseph Shrager
Joseph Shrager
Thoracic surgeon, Surgical oncologist
Professor of Cardiothoracic Surgery
Leah Backhus
Leah Backhus
Thoracic surgeon, Surgical oncologist, Thoracic specialist, Cardiothoracic surgeon
Thelma and Henry Doelger Professor of Cardiovascular Surgery

Contact us to find out if this trial is right for you.

Contact

Study Team
650-721-6561

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View on ClinicalTrials.gov