Outreach and Choice in Colorectal Cancer Screening

Trial ID or NCT#

NCT04940442

Status

not recruiting iconNOT RECRUITING

Purpose

The primary objective of this clinical trial will be to compare overall colorectal cancer (CRC) screening participation between an active choice (fecal immunochemical test \[FIT\] or colonoscopy) and a sequential choice (FIT offered first, then colonoscoscopy offered in those still unscreened) arm. Secondarily, we will (1) compare the proportions of FIT vs. colonoscopy per arm, (2) compare active choice vs FIT only in the initial 3 months of the study, (3) characterize changes in physician knowledge and attitudes regarding CRC screening before and after an educational seminar delivered at the launch of the initiative, (4) characterize perceptions regarding the effect of the intervention on clinical practices, and (5) compare detection rates of CRC, adenomas and SSLs per arm, and the operational results of the outreach program across arms.

Official Title

Outreach and Choice in Colorectal Cancer Screening

Eligibility Criteria

Ages Eligible for Study: 45 Years to 75 Years
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers: No
Inclusion Criteria:
  1. 1. Adults 45-75 years of age not up to date with CRC screening, and without precancerous polyp history (i.e. not in post-polypectomy surveillance; ascertained based on problem list or colonoscopy results letter).2. The assessment of screening status will happen monthly, on a rolling basis.3. Definition of being up to date with CRC screening includes any one of the following:
    1. i) FIT or guaiac-FOBT within 1 year, OR
    2. ii) Colonoscopy within 10 years, OR
    3. iii) Sigmoidoscopy within 5 years, OR
    4. iv) CT colonography within 5 years, OR
    5. v) Cologuard within 3 years
Exclusion Criteria:
  1. 1. Age outside the 45-75 range.2. History of precancerous polyps requiring colonoscopy surveillance.3. Already being up to date with CRC screening, as defined above.4. Evidence of total removal of the colon which would eliminate the need for screening.
View All Criteria
Show Less

Investigator(s)

Uri Ladabaum
Uri Ladabaum
Gastroenterologist, Geneticist, Cancer geneticist, General gastroenterologist
Professor of Medicine (Gastroenterology and Hepatology)

Contact us to find out if this trial is right for you.

Contact

Uri Ladabaum, MD
650-725-2850

View on ClinicalTrials.gov