Predicting Endometrial Receptivity for Optimal Reproductive Management
Trial ID or NCT#
Status
Purpose
The purpose of this study is to understand why some women are infertile (unable to conceive a child). The investigators hope to learn if an endometrial biopsy after egg retrieval is feasible for detecting biomarkers for endometriosis and predicting implantation and pregnancy rate after embryo transfer. This study design will provide for the first time, an opportunity to compare endometrial biopsy material from hyperstimulated (gonadotropin treated) subjects after egg retrieval. If successful, it would provide a new protocol for women with unexplained infertility or those with known endometriosis to avoid poor IVF outcomes.
Official Title
Predicting Endometrial Receptivity for Optimal Reproductive Management (PERFORM)
Eligibility Criteria
- 1. Age - 18 to 42 2. AMH ≥ 1 3. Planning to undergo IVF with delayed embryo transfer 4. Must have blastocyst(s) by day 6 that were biopsied for PGT-A 5. BMI 18-35
- 1. Uterine fibroids > 4 cm in size 2. Polycystic ovary syndrome (PCOS) according with the Rotterdam criteria. 3. Ovarian failure and subjects receiving donor oocytes/embryos 4. Anti-cardiolipid and/or lupus anti-coagulant abnormalities by history 5. Diabetes mellitus (Type I or Type II) 6. Untreated hypothyroidism 7. Hyperprolactinemia 8. Uncorrected uterine anomaly
Investigator(s)
Contact us to find out if this trial is right for you.
Contact
Raquel Fleischmann, DVM
408-426-5586
View on ClinicalTrials.gov