Peripheral Immune System in Individuals With Schizophrenia
Trial ID or NCT#
NCT05109065
Status
RECRUITING
Purpose
The investigators are seeking healthy volunteers and people with schizophrenia or schizoaffective disorder for a clinical study of the immune system in psychotic disorders. This is an observational study, to understand the ways in which the immune system may be contributing to the disease process.
Official Title
Peripheral Immune System in Individuals With Schizophrenia
Eligibility Criteria
Ages Eligible for Study: 18 to 40
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers: Yes
Inclusion Criteria:
- for Subjects with schizophrenia and schizoaffective disorders:
- * Schizophrenia or schizoaffective disorder diagnosis verified by interview* Diagnosis or initiation of antipsychotic medication was within last 5 years
- Inclusion Criteria for Healthy Controls:
- * No known diagnosis of schizophrenia or schizoaffective disorder* No history of depression, anxiety, bipolar disorder, PTSD, agoraphobia, panic disorder, or generalized anxiety disorder* Negative assessment for psychotic symptoms on day of interview
- Exclusion Criteria (for both groups):
- * Participants have a history of bleeding disorders or are taking blood thinners.* Participants have a history of epilepsy, known genetic disorders* Immunocompromised state (eg., receiving immunosuppressive therapy, transplant).* History of brain-related disease (eg., stroke)* Any uncontrolled medical disorder such as cancer.* History of substance abuse or positive urine toxicology screen (including test for marijuana) on the day of the blood draw
Exclusion Criteria:
- (for both groups):
- * Participants have a history of bleeding disorders or are taking blood thinners.* Participants have a history of epilepsy, known genetic disorders* Immunocompromised state (eg., receiving immunosuppressive therapy, transplant).* History of brain-related disease (eg., stroke)* Any uncontrolled medical disorder such as cancer.* History of substance abuse or positive urine toxicology screen (including test for marijuana) on the day of the blood draw
Investigator(s)
Agnieszka Kalinowski
Clinical Assistant Professor, Psychiatry and Behavioral Sciences
Contact us to find out if this trial is right for you.
Contact
Diane E Wakeham, PhD
650-736-5243
View on ClinicalTrials.gov
