Randomized Clinical Trial of Intranasal Injection of Platelet-Rich Plasma for Treatment of Parosmia

Trial ID or NCT#

NCT06283745

Status

recruiting iconRECRUITING

Purpose

This randomized clinical trial will evaluate the benefit of platelet-rich plasma (PRP) in the treatment of qualitative olfactory dysfunction (parosmia). PRP can be isolated from a patient's own blood and has been found in previous studies to have anti-inflammatory and pro-regenerative properties. It has been used across multiple specialties, such as Orthopedics, Facial Plastics, Dermatology, Neurology in injected form to treat a wide variety of tissues to encourage the body's inherent regenerative capacity. The investigators have completed a randomized controlled trial here, ending in 2022, evaluating it's use in post-SARS-CoV-2 olfactory loss which demonstrated safety and efficacy. Therefore, the investigators aim to assess the ability of PRP to improve olfactory function in patients with parosmia.

Official Title

Randomized Clinical Trial of Intranasal Injection of Platelet-Rich Plasma for Treatment of Parosmia

Eligibility Criteria

Sexes Eligible for Study: ALL
Accepts Healthy Volunteers: Yes

Investigator(s)

Zara M. Patel, MD
Zara M. Patel, MD
Head and neck surgeon, Otolaryngologist, Rhinologist, Smelling Disorders Specialist
Professor of Otolaryngology - Head & Neck Surgery (OHNS) and, by courtesy, of Neurosurgery

Contact us to find out if this trial is right for you.

Contact

Homer Abaya, BS
(650) 725-6500